Optimal Split Plot Overview
For a split-plot experiment with sample size n and b whole plots, the linear mixed model can be written as:
g = Xb + Zg + ε
where X represents the n×p fixed design matrix containing the settings of both the whole-plot factors w and the sub-plot factors s and their model expansions, b is a p-dimensional vector containing the p fixed effects in the model, Z is an n × b matrix of zeroes and ones assigning the n runs to the b whole plots, g is the b-dimensional vector containing the random effects of the b whole plots, and ε is the n-dimensional vector containing the random errors.
The following assumptions are made:
E(ε) = 0n and cov(ε) = s2ε ln,
E(g) = 0b and cov(g) = s2g lb,
cov(g,ε) = 0bxn
Under these assumptions, the covariance matrix of the responses, var(g), is:
V = s 2ε ln + s2g ZZ'
The generalized least squares estimator is:
= (X'V-1X)-1X'V-1g,
with covariance matrix:
var( ) = (X'V-1 X)-1
The information matrix on the unknown fixed parameters b is given by
M = X'V -1X
The D-optimality criterion seeks to maximize the determinant of this information matrix.
This is the criterion has been used for constructing split-plot designs by STATISTICA’s optimal split plot design module. For more detailed information see Bradley and Goos (2006).